Friday, May 25, 2007

Experience-dependent rescaling of entorhinal grids

Caswell Barry, Robin Hayman, Neil Burgess and Kathryn J Jeffery
Nature Neuroscience - 10, 682 - 684 (2007)
Published online: 7 May 2007; | doi:10.1038/nn1905

The firing pattern of entorhinal 'grid cells' is thought to provide an intrinsic metric for space. We report a strong experience-dependent environmental influence: the spatial scales of the grids (which are aligned and have fixed relative sizes within each animal) vary parametrically with changes to a familiar environment's size and shape. Thus grid scale reflects an interaction between intrinsic, path-integrative calculation of location and learned associations to the external environment.


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